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Title: Fabrication of Antibacterial Silver Nanoparticle‐Modified Chitosan Fibers Using Eucalyptus Extract as a Reducing Agent
Journal: Journal of Applied Polymer Science
Author: 1. Mansoor Arvand, Esmaeil Mirzaei, Mohammad Ali Derakhshan, Sharmin Kharrazi, Esmaeil Sadroddiny, Reza Faridi-Majidi, 2. Mahmoud Babapour
Year: 2015
Address: 1. Department of Medical Nanotechnology, School of Advanced Technologies in Medicine, Tehran University of Medical Sciences, Tehran, Iran 2. Medical Laboratory of Central Farhangian Clinic, Tehran, Iran
Abstract: Green chemical method could be a promising route to achieve large scale synthesis of nanostructures for biomedical applications. Here, we describe a green chemical synthesis of silver nanoparticles (Ag NPs) on chitosan-based electrospun nanofibers using Eucalyptus leaf extract. A series of silver salt (AgNO3) amounts were added to a certain composition of chitosan/polyethylene oxide aqueous acetic acid solution. The solutions were then electrospun to obtain nanofibrous mats and then, morphology and size of nanofibers were analyzed by scanning electron microscopy (SEM). Incubation of AgNO3-containing mats into Eucalyptus leaf extract led to the formation of Ag NP clusters with average diameter of 91624 nm, depicted by SEM and transmission electron microscopy. Surface enhanced Raman spectroscopy also confirmed formation of Ag NPs on the nanofibers. The mats also showed antimicrobial activity against Escherichia coli and Staphylococcus aureus bacteria with bigger inhibition zone for extract-exposed mats against S. aureus.
Keywords: biomedical applications; electrospinning; fibers; nanoparticles; nanowires and nanocrystals
Application: Antibacterial Properties
Product Model 1: Electroris
Product Model 2:
URL: http://onlinelibrary.wiley.com/doi/10.1002/app.42133/full#="http://onlinelibrary.wiley.com" & "/doi/10.1002/app.42133/full"#